Raymond F Regan Selected Research

Hemin (Panhematin)

1/2017	Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage.
1/2015	Targeting heme oxygenase after intracerebral hemorrhage.
10/2014	Systemic hemin therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage.
5/2006	Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury.
12/2005	Cultured astrocytes from heme oxygenase-1 knockout mice are more vulnerable to heme-mediated oxidative injury.
7/2005	Increasing expression of heme oxygenase-1 by proteasome inhibition protects astrocytes from heme-mediated oxidative injury.
11/2004	Adenoviral transfer of the heme oxygenase-1 gene protects striatal astrocytes from heme-mediated oxidative injury.
9/2004	Heme oxygenase-2 gene deletion attenuates oxidative stress in neurons exposed to extracellular hemin.
7/2003	Hemin induces an iron-dependent, oxidative injury to human neuron-like cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Raymond F Regan Research Topics

Disease

15	Hemorrhage 01/2018 - 07/2003
14	Cerebral Hemorrhage 01/2021 - 03/2007
6	Wounds and Injuries (Trauma) 01/2017 - 01/2003
6	Hematoma 01/2015 - 07/2003
4	Hemorrhagic Stroke 01/2021 - 01/2003
3	Hemolysis 11/2016 - 08/2010
3	Inflammation (Inflammations) 12/2009 - 11/2006
2	Stroke (Strokes) 01/2021 - 04/2012
2	Vascular System Injuries 01/2018 - 02/2008
2	Acute Intermittent Porphyria (Porphyria, Acute) 01/2017 - 10/2014
2	Sickle Cell Anemia (Hemoglobin S Disease) 04/2011 - 05/2004
1	Ischemic Stroke 01/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020
1	Thrombosis (Thrombus) 01/2020
1	Edema (Dropsy) 01/2018
1	Multiple Sclerosis 01/2017
1	Malaria 12/2015
1	Infections 12/2015
1	Falciparum Malaria (Plasmodium falciparum Malaria) 12/2015
1	Peritonitis 11/2006
1	Seizures (Absence Seizure) 05/2006
1	Hyperglycemia 04/2006
1	Weight Loss (Weight Reduction) 11/2005
1	Alzheimer Disease (Alzheimer's Disease) 10/2005
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 10/2005

Drug/Important Bio-Agent (IBA)

12	Hemoglobins (Hemoglobin)IBA 01/2021 - 01/2003
11	Heme (Haem)IBA 01/2021 - 10/2003
9	Hemin (Panhematin)FDA Link 01/2017 - 07/2003
7	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 01/2017 - 10/2003
5	HemopexinIBA 01/2021 - 04/2011
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2006
5	Heme Oxygenase-1IBA 01/2020 - 11/2004
5	Collagenases (Collagenase)FDA Link 01/2019 - 06/2010
4	heme oxygenase-2IBA 08/2014 - 11/2005
4	IronIBA 02/2011 - 04/2009
3	HaptoglobinsIBA 01/2018 - 12/2015
3	Chelating AgentsIBA 12/2011 - 10/2005
2	Oxidants (Oxidizing Agents)IBA 05/2006 - 09/2004
2	NeurotoxinsIBA 11/2004 - 01/2003
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Heme-Binding ProteinsIBA 01/2020
1	AntioxidantsIBA 06/2017
1	Glial Fibrillary Acidic ProteinIBA 06/2017
1	EnzymesIBA 01/2017
1	CXCR3 ReceptorsIBA 01/2017
1	Chemokine CXCL11IBA 01/2017
1	Dimethyl FumarateIBA 01/2017
1	Therapeutic UsesIBA 11/2016
1	CollagenIBA 12/2014
1	CXC ChemokinesIBA 12/2014
1	Evans Blue (Blue, Evans)FDA Link 10/2014
1	Neuroprotective AgentsIBA 08/2014
1	Thrombin FDA Link 12/2012
1	apotransferrinIBA 02/2011
1	Deferoxamine (Desferal)FDA LinkGeneric 08/2010
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 08/2010
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 08/2010
1	Dizocilpine Maleate (Dizocilpine)IBA 08/2010
1	Ferritins (Ferritin)IBA 06/2010
1	Minocycline (Cyclops)FDA LinkGeneric 08/2009
1	Interleukin-18 (Interleukin 18)IBA 02/2008
1	AntigensIBA 11/2006
1	CytokinesIBA 11/2006
1	Glutamic Acid (Glutamate)FDA Link 05/2006
1	Neurotransmitter Agents (Neurotransmitter)IBA 05/2006
1	Streptozocin (Streptozotocin)FDA Link 04/2006
1	CreatinineIBA 04/2006
1	stroma free hemoglobinIBA 11/2005
1	Amyloid beta-PeptidesIBA 10/2005
1	MetalsIBA 10/2005
1	Clioquinol (Vioform)FDA Link 10/2005
1	Hemoglobin AIBA 05/2004
1	Sickle HemoglobinIBA 05/2004

Therapy/Procedure

5	Therapeutics 01/2021 - 12/2011
1	Thrombectomy 01/2021
1	Ligation 01/2020
1	Drug Therapy (Chemotherapy) 06/2017